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\u092f\u0939 \u0926\u0943\u0937\u094d\u091f\u093f\u0915\u094b\u0923 \u0905\u0927\u093f\u0915 \u0938\u0930\u0932 \u0914\u0930 \u0924\u0947\u091c\u093c \u0909\u092a\u091a\u093e\u0930 \u0915\u0947 \u092e\u093e\u0930\u094d\u0917 \u0915\u094b \u0916\u094b\u0932\u0924\u093e \u0939\u0948\u0964 \u092f\u0939 \u092a\u094d\u0930\u092f\u094b\u0917\u0936\u093e\u0932\u093e \u092e\u0947\u0902 \u0915\u094b\u0936\u093f\u0915\u093e\u0913\u0902 \u0915\u094b \u0928\u093f\u0915\u093e\u0932\u0928\u0947 \u0914\u0930 \u0938\u0902\u0935\u0930\u094d\u0927\u0928 \u0915\u0930\u0928\u0947 \u0915\u0947 \u091a\u0930\u0923\u094b\u0902 \u0938\u0947 \u092c\u091a\u0924\u093e \u0939\u0948, \u091c\u093f\u0938\u0938\u0947 \u0932\u093e\u0917\u0924 \u0914\u0930 \u0938\u092e\u092f \u0915\u092e \u0939\u094b\u0924\u093e \u0939\u0948\u0964 \u0907\u0938\u0915\u0947 \u0905\u0932\u093e\u0935\u093e, \u092f\u0939 \u0905\u0928\u094d\u092f \u092c\u0940\u092e\u093e\u0930\u093f\u092f\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u092d\u0940 \u0905\u0928\u0941\u0915\u0942\u0932\u093f\u0924 \u0915\u093f\u092f\u093e \u091c\u093e \u0938\u0915\u0924\u093e \u0939\u0948 \u091c\u0939\u093e\u0902 \u091f\u0940-\u0915\u094b\u0936\u093f\u0915\u093e\u090f\u0902 \u092e\u0939\u0924\u094d\u0935\u092a\u0942\u0930\u094d\u0923 \u092d\u0942\u092e\u093f\u0915\u093e \u0928\u093f\u092d\u093e\u0924\u0940 \u0939\u0948\u0902, \u091c\u0948\u0938\u0947 \u0938\u0902\u0915\u094d\u0930\u092e\u0923 \u092f\u093e \u0911\u091f\u094b\u0907\u092e\u094d\u092f\u0942\u0928 \u092c\u0940\u092e\u093e\u0930\u093f\u092f\u093e\u0902\u0964<\/p>\n

\u091a\u0942\u0939\u094b\u0902 \u092e\u0947\u0902 \u092a\u094d\u0930\u093e\u092a\u094d\u0924 \u092a\u0930\u093f\u0923\u093e\u092e \u0906\u0936\u093e\u091c\u0928\u0915 \u0939\u0948\u0902, \u0932\u0947\u0915\u093f\u0928 \u092e\u093e\u0928\u0935 \u092e\u0947\u0902 \u0907\u0938\u0915\u0947 \u092a\u094d\u0930\u092d\u093e\u0935\u0915\u093e\u0930\u093f\u0924\u093e \u0914\u0930 \u0938\u0941\u0930\u0915\u094d\u0937\u093e \u0915\u0940 \u092a\u0941\u0937\u094d\u091f\u093f \u0915\u0930\u0928\u0947 \u0915\u0947 \u0932\u093f\u090f \u0914\u0930 \u0905\u0927\u094d\u092f\u092f\u0928 \u0915\u0940 \u0906\u0935\u0936\u094d\u092f\u0915\u0924\u093e \u0939\u094b\u0917\u0940\u0964 \u092f\u0926\u093f \u092f\u0947 \u092a\u0930\u0940\u0915\u094d\u0937\u0923 \u0938\u092b\u0932 \u0939\u094b\u0924\u0947 \u0939\u0948\u0902, \u0924\u094b \u092f\u0939 \u0924\u0915\u0928\u0940\u0915 \u0915\u0908 \u0930\u094b\u0917\u093f\u092f\u094b\u0902 \u0915\u0947 \u0932\u093f\u090f \u0915\u094b\u0936\u093f\u0915\u093e \u0925\u0947\u0930\u0947\u092a\u0940 \u0924\u0915 \u092a\u0939\u0941\u0902\u091a \u0915\u094b \u0915\u094d\u0930\u093e\u0902\u0924\u093f\u0915\u093e\u0930\u0940 \u092c\u0928\u093e \u0938\u0915\u0924\u0940 \u0939\u0948\u0964<\/p>\n

\n

\u0938\u093e\u092e\u0917\u094d\u0930\u0940 \u0938\u0902\u0926\u0930\u094d\u092d<\/h2>\n

\u0906\u0927\u093f\u0915\u093e\u0930\u093f\u0915 \u0938\u0902\u0926\u0930\u094d\u092d<\/h3>\n

DOI:<\/strong> https:\/\/doi.org\/10.1038\/s41586-026-10235-x<\/a><\/p>\n

\u0936\u0940\u0930\u094d\u0937\u0915:<\/strong> In vivo site-specific engineering to reprogram T cells<\/p>\n

\u091c\u0930\u094d\u0928\u0932:<\/strong> Nature<\/p>\n

\u092a\u094d\u0930\u0915\u093e\u0936\u0915:<\/strong> Springer Science and Business Media LLC<\/p>\n

\u0932\u0947\u0916\u0915:<\/strong> William A. Nyberg; Pierre-Louis Bernard; Wayne Ngo; Charlotte H. Wang; Jonathan Ark; Allison Rothrock; Gina M. Borgo; Gabriella R. Kimmerly; Jae Hyung Jung; Vincent Allain; Jennifer R. Hamilton; Alisha Baldwin; Robert Stickels; Sarah Wyman; Safwaan H. Khan; Shanshan Lang; Donna Marsh; Niran Almudhfar; Catherine Novick; Yasaman Mortazavi; Shimin Zhang; Mahmoud M. AbdElwakil; Luis R. Sandoval; Sidney Hwang; Simon N. Chu; Hyuncheol Jung; Chang Liu; Devesh Sharma; Travis McCreary; Zhongmei Li; Ansuman T. Satpathy; Julia Carnevale; Rachel L. Rutishauser; M. Kyle Cromer; Kole T. Roybal; Stacie E. Dodgson; Jennifer A. Doudna; Aravind Asokan; Justin Eyquem<\/p>\n","protected":false},"excerpt":{"rendered":"

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