{"id":19,"date":"2026-06-11T12:17:53","date_gmt":"2026-06-11T10:17:53","guid":{"rendered":"https:\/\/theengineeringreview.com\/vi\/2026\/06\/11\/oligosaccharide-tien-sinh-hoc-cai-thien-suc-khoe-duong-ruot-va-chuyen-hoa\/"},"modified":"2026-06-11T12:18:35","modified_gmt":"2026-06-11T10:18:35","slug":"oligosaccharide-tien-sinh-hoc-cai-thien-suc-khoe-duong-ruot-va-chuyen-hoa","status":"publish","type":"post","link":"https:\/\/theengineeringreview.com\/vi\/2026\/06\/11\/oligosaccharide-tien-sinh-hoc-cai-thien-suc-khoe-duong-ruot-va-chuyen-hoa\/","title":{"rendered":"Oligosaccharide ti\u1ec1n sinh h\u1ecdc c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe \u0111\u01b0\u1eddng ru\u1ed9t v\u00e0 chuy\u1ec3n h\u00f3a"},"content":{"rendered":"

\"Oligosaccharide“`html<\/p>\n

Oligosaccharide ti\u1ec1n sinh h\u1ecdc c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe \u0111\u01b0\u1eddng ru\u1ed9t v\u00e0 chuy\u1ec3n h\u00f3a<\/h1>\n

Oligosaccharide ti\u1ec1n sinh h\u1ecdc, ch\u1eb3ng h\u1ea1n nh\u01b0 inulin ho\u1eb7c fructo-oligosaccharide, \u0111ang thay \u0111\u1ed5i b\u1ec1n v\u1eefng s\u1ee9c kh\u1ecfe ti\u00eau h\u00f3a v\u00e0 to\u00e0n di\u1ec7n. Nh\u1eefng h\u1ee3p ch\u1ea5t n\u00e0y, c\u00f3 t\u1ef1 nhi\u00ean trong c\u00e1c th\u1ef1c ph\u1ea9m nh\u01b0 t\u1ecfi, h\u00e0nh, chu\u1ed1i ho\u1eb7c c\u00fac vu, k\u00edch th\u00edch c\u00f3 ch\u1ecdn l\u1ecdc s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a vi khu\u1ea9n c\u00f3 l\u1ee3i trong ru\u1ed9t, \u0111\u1eb7c bi\u1ec7t l\u00e0 bifidobacteria v\u00e0 lactobacilli. S\u1ef1 l\u00ean men c\u1ee7a ch\u00fang b\u1edfi h\u1ec7 vi sinh v\u1eadt s\u1ea3n sinh ra c\u00e1c axit b\u00e9o chu\u1ed7i ng\u1eafn, ch\u1eb3ng h\u1ea1n nh\u01b0 acetate, propionate v\u00e0 butyrate, r\u1ea5t quan tr\u1ecdng \u0111\u1ec3 c\u1ee7ng c\u1ed1 h\u00e0ng r\u00e0o ru\u1ed9t, gi\u1ea3m vi\u00eam v\u00e0 \u0111i\u1ec1u ch\u1ec9nh h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch.<\/p>\n

Nh\u1eefng axit b\u00e9o n\u00e0y \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c b\u1ea3o v\u1ec7 ni\u00eam m\u1ea1c ru\u1ed9t, b\u1eb1ng c\u00e1ch duy tr\u00ec \u0111\u1ed9 pH c\u00e2n b\u1eb1ng v\u00e0 h\u1ea1n ch\u1ebf s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a vi sinh v\u1eadt c\u00f3 h\u1ea1i. Ch\u00fang c\u0169ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a n\u0103ng l\u01b0\u1ee3ng v\u00e0 s\u1ef1 giao ti\u1ebfp gi\u1eefa ru\u1ed9t v\u1edbi c\u00e1c c\u01a1 quan kh\u00e1c, ch\u1eb3ng h\u1ea1n nh\u01b0 n\u00e3o ho\u1eb7c gan. V\u00ed d\u1ee5, vi\u1ec7c s\u1ea3n sinh nhi\u1ec1u propionate trong \u0111\u1ea1i tr\u00e0ng c\u00f3 th\u1ec3 gi\u1ea3m t\u00edch t\u1ee5 ch\u1ea5t b\u00e9o trong gan, trong khi butyrate nu\u00f4i d\u01b0\u1ee1ng c\u00e1c t\u1ebf b\u00e0o \u0111\u1ea1i tr\u00e0ng v\u00e0 \u0111i\u1ec1u ch\u1ec9nh bi\u1ec3u hi\u1ec7n c\u1ee7a c\u00e1c gen li\u00ean quan \u0111\u1ebfn mi\u1ec5n d\u1ecbch.<\/p>\n

Oligosaccharide kh\u00f4ng ch\u1ec9 t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn ti\u00eau h\u00f3a. Ch\u00fang c\u1ea3i thi\u1ec7n k\u1ebft c\u1ea5u, \u0111\u1ed9 ng\u1ecdt v\u00e0 \u0111\u1ed9 \u1ed5n \u0111\u1ecbnh c\u1ee7a c\u00e1c th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng, \u0111\u1ed3ng th\u1eddi gi\u1eef nguy\u00ean c\u00e1c \u0111\u1eb7c t\u00ednh sinh h\u1ecdc c\u1ee7a ch\u00fang. C\u00e1c k\u1ef9 thu\u1eadt hi\u1ec7n \u0111\u1ea1i, ch\u1eb3ng h\u1ea1n nh\u01b0 bao g\u00f3i vi nang, b\u1ea3o v\u1ec7 nh\u1eefng h\u1ee3p ch\u1ea5t n\u00e0y kh\u1ecfi s\u1ef1 ph\u00e2n h\u1ee7y trong qu\u00e1 tr\u00ecnh ti\u00eau h\u00f3a, \u0111\u1ea3m b\u1ea3o gi\u1ea3i ph\u00f3ng c\u00f3 m\u1ee5c ti\u00eau trong \u0111\u1ea1i tr\u00e0ng. Khi k\u1ebft h\u1ee3p v\u1edbi probiotic trong c\u00e1c c\u00f4ng th\u1ee9c synbiotic, ch\u00fang t\u0103ng c\u01b0\u1eddng hi\u1ec7u qu\u1ea3 b\u1eb1ng c\u00e1ch th\u00fac \u0111\u1ea9y s\u1ef1 \u0111\u1ecbnh c\u01b0 b\u1ec1n v\u1eefng c\u1ee7a vi khu\u1ea9n c\u00f3 l\u1ee3i.<\/p>\n

T\u00e1c \u0111\u1ed9ng \u0111i\u1ec1u tr\u1ecb c\u1ee7a ch\u00fang m\u1edf r\u1ed9ng \u0111\u1ebfn vi\u1ec7c qu\u1ea3n l\u00fd c\u00e1c r\u1ed1i lo\u1ea1n \u0111a d\u1ea1ng. Ch\u00fang l\u00e0m gi\u1ea3m c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a h\u1ed9i ch\u1ee9ng ru\u1ed9t k\u00edch th\u00edch, t\u00e1o b\u00f3n ho\u1eb7c c\u00e1c b\u1ec7nh vi\u00eam ru\u1ed9t m\u1ea1n t\u00ednh b\u1eb1ng c\u00e1ch kh\u00f4i ph\u1ee5c s\u1ef1 c\u00e2n b\u1eb1ng c\u1ee7a h\u1ec7 vi sinh v\u1eadt v\u00e0 gi\u1ea3m vi\u00eam. Trong l\u0129nh v\u1ef1c chuy\u1ec3n h\u00f3a, m\u1ed9t s\u1ed1 oligosaccharide gi\u00fap ch\u1ed1ng b\u00e9o ph\u00ec v\u00e0 ti\u1ec3u \u0111\u01b0\u1eddng b\u1eb1ng c\u00e1ch c\u1ea3i thi\u1ec7n \u0111\u1ed9 nh\u1ea1y c\u1ea3m v\u1edbi insulin, \u0111i\u1ec1u ch\u1ec9nh \u0111\u01b0\u1eddng huy\u1ebft v\u00e0 \u0111i\u1ec1u ch\u1ec9nh s\u1ef1 l\u01b0u tr\u1eef lipid. T\u00e1c \u0111\u1ed9ng c\u1ee7a ch\u00fang l\u00ean tr\u1ee5c ru\u1ed9t-n\u00e3o c\u0169ng m\u1edf ra nh\u1eefng tri\u1ec3n v\u1ecdng cho vi\u1ec7c \u0111i\u1ec1u tr\u1ecb c\u00e1c r\u1ed1i lo\u1ea1n tho\u00e1i h\u00f3a th\u1ea7n kinh ho\u1eb7c c\u00e1c r\u1ed1i lo\u1ea1n t\u00e2m l\u00fd, ch\u1eb3ng h\u1ea1n nh\u01b0 tr\u1ea7m c\u1ea3m ho\u1eb7c lo \u00e2u, b\u1eb1ng c\u00e1ch t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn s\u1ef1 s\u1ea3n sinh c\u00e1c ch\u1ea5t d\u1eabn truy\u1ec1n th\u1ea7n kinh nh\u01b0 serotonin.<\/p>\n

Tuy nhi\u00ean, vi\u1ec7c s\u1eed d\u1ee5ng ch\u00fang kh\u00f4ng ph\u1ea3i l\u00e0 kh\u00f4ng c\u00f3 th\u00e1ch th\u1ee9c. Ti\u00eau th\u1ee5 qu\u00e1 m\u1ee9c c\u00f3 th\u1ec3 g\u00e2y \u0111\u1ea7y h\u01a1i ho\u1eb7c sinh kh\u00ed, \u0111\u1eb7c bi\u1ec7t \u1edf nh\u1eefng ng\u01b0\u1eddi nh\u1ea1y c\u1ea3m ho\u1eb7c m\u1eafc c\u00e1c v\u1ea5n \u0111\u1ec1 ti\u00eau h\u00f3a. S\u1ef1 bi\u1ebfn \u0111\u1ed5i c\u00e1 nh\u00e2n c\u1ee7a h\u1ec7 vi sinh v\u1eadt c\u0169ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 c\u1ee7a ch\u00fang, \u0111\u00f2i h\u1ecfi ph\u1ea3i c\u00f3 c\u00e1ch ti\u1ebfp c\u1eadn c\u00e1 nh\u00e2n h\u00f3a. Chi ph\u00ed s\u1ea3n xu\u1ea5t, nh\u1eefng th\u00e1ch th\u1ee9c c\u00f4ng ngh\u1ec7 trong vi\u1ec7c s\u1ea3n xu\u1ea5t \u1edf quy m\u00f4 l\u1edbn v\u00e0 c\u00e1c quy \u0111\u1ecbnh nghi\u00eam ng\u1eb7t v\u1ec1 tuy\u00ean b\u1ed1 s\u1ee9c kh\u1ecfe v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf vi\u1ec7c \u00e1p d\u1ee5ng r\u1ed9ng r\u00e3i ch\u00fang.<\/p>\n

Nh\u1eefng \u0111\u1ed5i m\u1edbi g\u1ea7n \u0111\u00e2y, ch\u1eb3ng h\u1ea1n nh\u01b0 vi\u1ec7c s\u1eed d\u1ee5ng tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o \u0111\u1ec3 d\u1ef1 \u0111o\u00e1n ph\u1ea3n \u1ee9ng c\u00e1 nh\u00e2n ho\u1eb7c ph\u00e1t tri\u1ec3n c\u00e1c ti\u1ec1n sinh h\u1ecdc th\u1ebf h\u1ec7 m\u1edbi, h\u1ee9a h\u1eb9n s\u1ebd t\u1ed1i \u01b0u h\u00f3a vi\u1ec7c s\u1eed d\u1ee5ng ch\u00fang. Nh\u1eefng ti\u1ebfn b\u1ed9 n\u00e0y c\u00f3 th\u1ec3 cho ph\u00e9p nh\u1eafm m\u1ee5c ti\u00eau ch\u00ednh x\u00e1c nhu c\u1ea7u c\u1ee7a m\u1ed7i ng\u01b0\u1eddi, d\u1ef1a tr\u00ean h\u1ec7 vi sinh v\u1eadt c\u1ee7a h\u1ecd, v\u00e0 m\u1edf r\u1ed9ng c\u00e1c \u1ee9ng d\u1ee5ng c\u1ee7a ch\u00fang trong th\u1ef1c ph\u1ea9m ch\u1ee9c n\u0103ng v\u00e0 li\u1ec7u ph\u00e1p. Nh\u01b0 v\u1eady, oligosaccharide ti\u1ec1n sinh h\u1ecdc kh\u1eb3ng \u0111\u1ecbnh m\u00ecnh l\u00e0 nh\u1eefng \u0111\u1ed3ng minh quan tr\u1ecdng cho s\u1ee9c kh\u1ecfe ph\u00f2ng ng\u1eeba v\u00e0 c\u00e1 nh\u00e2n h\u00f3a.<\/p>\n

“`<\/p>\n

\n

R\u00e9f\u00e9rences des contenus<\/h2>\n

R\u00e9f\u00e9rence officielle<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1007\/s13205-026-04776-1<\/a><\/p>\n

Titre\u00a0:<\/strong> Oligosaccharide prebiotics in functional foods and therapeutics: innovations and challenges<\/p>\n

Revue : <\/strong> 3 Biotech<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> K. S. Sandra; Megh Pravin Vithalkar; Vishnusai Beere; H. B. Bharath; B. Satyanarayana; Mohamed Rafiq; Yogendra Nayak<\/p>\n","protected":false},"excerpt":{"rendered":"

“`html Oligosaccharide ti\u1ec1n sinh h\u1ecdc c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe \u0111\u01b0\u1eddng ru\u1ed9t v\u00e0 chuy\u1ec3n h\u00f3a Oligosaccharide ti\u1ec1n sinh h\u1ecdc, ch\u1eb3ng h\u1ea1n nh\u01b0 inulin ho\u1eb7c fructo-oligosaccharide, \u0111ang thay \u0111\u1ed5i b\u1ec1n v\u1eefng s\u1ee9c kh\u1ecfe ti\u00eau h\u00f3a v\u00e0 to\u00e0n di\u1ec7n. Nh\u1eefng h\u1ee3p ch\u1ea5t n\u00e0y, c\u00f3 t\u1ef1 nhi\u00ean trong c\u00e1c th\u1ef1c ph\u1ea9m nh\u01b0 t\u1ecfi, h\u00e0nh, chu\u1ed1i ho\u1eb7c c\u00fac vu, k\u00edch… Continue reading Oligosaccharide ti\u1ec1n sinh h\u1ecdc c\u1ea3i thi\u1ec7n s\u1ee9c kh\u1ecfe \u0111\u01b0\u1eddng ru\u1ed9t v\u00e0 chuy\u1ec3n h\u00f3a<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3],"tags":[],"class_list":["post-19","post","type-post","status-publish","format-standard","hentry","category-suc-khoe","entry"],"_links":{"self":[{"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/posts\/19","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/comments?post=19"}],"version-history":[{"count":1,"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/posts\/19\/revisions"}],"predecessor-version":[{"id":20,"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/posts\/19\/revisions\/20"}],"wp:attachment":[{"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/media?parent=19"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/categories?post=19"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theengineeringreview.com\/vi\/wp-json\/wp\/v2\/tags?post=19"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}